BioProcess Digital Courses
Microbial fermentation processes
Learn how to scale-up and optimize microbial fermentors
The course teaches the simulation based scale-up and optimization of microbial fermentors. It first describes the kinetic analysis and modeling-simulation at the laboratory. Then, at the industrial scale, the optimization of the fermentor operational mode and variables. The methodology is learned through a R&D project on glutamic acid fermentation
WHAT YOU'LL LEARN ?
Design and analyze experiments to determine the kinetics of microbial reactions
Construct fermentors simulation models in batch, continuous and fed-batch operations
Use process simulators to scale up, design and optimize microbial fermentors for highest productivity or lowest production cost
What are fermentors productivity limitations by microbial reaction, oxygen and heat transfers ?
VIRTUAL R&D PROJECT
Design and optimal operation of a glutamic acid fermentation process
Kinetic analysis of Corynebacteria growth and metabolism
Simulation model of glutamic acid fermentation
Cost evaluation of glutamic acid production process
Optimal operation of batch, continuous and fed-batch fermentors
Fermentation intensification by oxygen-enriched air and membrane perfusion